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If you would like additional information regarding AstraZeneca's products, please contact the Information Center at AstraZeneca in the U.S. at 1-800-236-9933, Monday through Friday 8am - 6pm ET, excluding holidays.

NEXIUM is prescribed to treat the symptoms of acid reflux disease, which typically include persistent heartburn on 2 or more days per week, despite treatment and change of diet.

For many people, NEXIUM is also prescribed to heal damage to the esophagus called erosive esophagitis. This damage may be caused over time from stomach acid wearing away the lining of the esophagus. Only a doctor can diagnose this condition. With NEXIUM, most erosions heal in 4 to 8 weeks. Your results with NEXIUM may vary.

Side effects with NEXIUM include headache, diarrhea, and abdominal pain. Symptom relief does not rule out other serious stomach conditions.

Please read the Important Product Information and discuss it with your doctor or health care professional.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

©2008 AstraZeneca LP. All rights reserved. 262263 6/08
This product information is intended for US consumers only. NEXIUM and the color purple as applied to the capsule are registered trademarks and Purple Plus is a trademark of the AstraZeneca group of companies.